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Signals Screening

Lab data management & analysis for all modalities in one platform

Signals Screening unites assay development, low throughput to ultra-high throughput production assays, High Content Screening, and in vivo studies so users can search across all assay and screening data in a single platform.

Signals Screening

PerkinElmer Enterprise Scientific Research Solutions

Assay Development Data Management & Analysis

Signals Screening is flexible enough for one-off assay work during assay development, comprehensive enough for more sophisticated assays, and diverse enough to support a long and growing list of techniques and that is scalable all the way to ultra-high data volumes. Scientists can now leverage a consistent , repeatable pattern for data acquisition as well as the data processing protocols themselves.

Intuitive Data Capture

  • Intuitive apps for all assay instruments dataWoven together into guided workflows
  • Parsers with easy configuration options No IT dependency
  • Batch import files optionExtract metadata from header and footer rows, columns, or cells
  • Plate map or layout information can be created or applied
  • From instrument data import to reporting in minutes

Configurable Calculation Engine

  • Pick and Choose Equations, Apply at Any Scope
  • All Graphpad PRISM equations and more
  • Local and global curve fits in minutes
  • From one-off curve fits to millions in minutes
  • Calculated columns, and custom calculations- ad hoc
  • Saved analysis available to be applied to new/ high throughput/ historical data
  • Reports with curve fit thumbnails

Store & Search All Assay Parameters

  • Optimize Assay Development
  • All assay parameters are stored and indexed for search
  • Includes data from HTS, DMPK, to in vivo safety and efficacy studies.
  • Fast and Intuitive entity centric search
  • Quick and easy structure activity relationship analysis for small and large molecules

Unique Data Handling for In vivo/ DMPK

  • Never-before Cross Study Analytics
  • Design studies, cohorts etc. without dependency on IT
  • Built for purpose to address specific requirements for handling studies, treatments, samples
  • Integrate In vitro & In vivo data to generate novel candidate nomination visualizations
  • Ideal for data analytics of all therapeutic areas

Improve the drug discovery tool box

From a comprehensive library of techniques for assay development, to HTS data management and analysis, to in vivo data management and analysis, Signals Screening provides the tools you need.

Protocol Templates

Save and Share Protocols

From day to day, between and across groups.

Less human configuring, less human error.

One software package for multiple instruments and assay types.

Less time getting up to speed on multiple instrument software packages.

Parsers with easy configuration options

Onboard new techniques quickly

Comprehensive Analytics

Integration with TIBCO® Spotfire® allows for nearly limitless visualization capabilities.

Interactive visualizations.

Standard Statistical Analyses driven by TIBCO® Spotfire.®

Out of the box equations or create custom ones on the fly.

Search and Publish

Consistent metadata application to all screening data

Easily publish analysis to Signals Data Factory

Fast and Intuitive entity centric search

A Complete BioELN Solution

Only a truly integrated solution provides enterprise biology organizations the orchestrated workflows that drive better decision-making. The PerkinElmer BioELN solution provides the unique set of capabilities necessary to achieve this goal. It combines workflow support; documentation and collaboration capabilities; instrument integration and data processing; animal studies data management; curve fitting, data analysis, and materials management – all unified in a single platform.

Columbus Image Data Storage and Analysis

The ColumbusTM Image Data Storage and Analysis Solution is integrated into Signals Screening to support High Content Screening and Phenoytic Screening data analysis. It has functions like remote access, viewing, annotating, and measuring multidimensional images together with your phenotypic screening results from anywhere. You can numerically express the differences between cell intensity, morphology and even features you can’t see, like texture. Whether working in 2D or 3D, now you can focus on your science, gain insight sooner, easily translate in vitro models into in vivo results, and succeed faster. Find out more about the Columbus integration here.

What’s New with Signals Screening?

Signals Screening is continuously improved to ensure our customers have the best screening solution around. Find out about all the latest improvements.

Scientific data processing tools must offer flexibility, usability, and reproducibility.These critical capabilities are always in tension with one another. Existing tools tend to compromise. Generic tools like Excel, Graph Pad, or MiniTab offer great flexibility but sacrifice ease of use the data governance required for scientific reproducibility. Bespoke tools on the other hand provide targeted solutions for very specific scenarios but lack the flexibility required by the ad-hoc nature of scientific discovery.

The Signals Screening platform is the first in the industry to offer the ideal balance.It is based on the highly flexible and extensible Spotfire analytics platform. This allows extensive configurability and interoperability with third-party and open source libraries. But unlike monolithic bespoke applications, it is fully modular. Task-specific Spotfire Applications provide out-of-the-box modules of advanced scientific functionality that can be composed into self-documented and fully reproducible versioned data processing protocols. New functionality can be readily added to the application without costly custom feature development.

Signals Screening Data Sheet
Signals Screening SPR Data Sheet
Improve the Drug Discovery Toolbox
Creating the New Gold Standard in Assay Data Management & Analysis
A Demonstration of Signals™ Screening
Is Your Scientific Research Platform Helping You Make The Right Decisions?
How a Top Pharma Pressure Tests a New Platform to Unify Diverse R&D Data Analytics
How to optimize in vitro and in vivo data analysis
What’s New with Signals Screening
Signals Screening Launch Services
Interview with Nature Magazine

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